No, not if you have followed below instructions-
1. You have not change any SEO keywords of your website.
Ex. if product1 has this URL before www.yousite.com/product1, the new URL must be same.
2. You have not made any change in HTML part of the front end.
Ex. H1 Tags on all pages, meta properties (like meta keywords, meta title, meta description) , main images on product pages, SEO contents on your pages like category description on category page, product description on product page, schema tags etc.
3. Design changes does not affect the SEO.
Suggestions for good SEO